Journal article

Blue-light filtering intraocular lenses (IOLs) for protecting macular health

Laura E Downie, Ljoudmila Busija, Peter R Keller

COCHRANE DATABASE OF SYSTEMATIC REVIEWS | WILEY | Published : 2018

Abstract

Background: An intraocular lens (IOL) is a synthetic lens that is surgically implanted within the eye following removal of the crystalline lens, during cataract surgery. While all modern IOLs attenuate the transmission of ultra-violet (UV) light, some IOLs, called blue-blocking or blue-light filtering IOLs, also reduce short-wavelength visible light transmission. The rationale for blue-light filtering IOLs derives primarily from cell culture and animal studies, which suggest that short-wavelength visible light can induce retinal photoxicity. Blue-light filtering IOLs have been suggested to impart retinal protection and potentially prevent the development and progression of age-related macula..

View full abstract

University of Melbourne Researchers

Grants

Awarded by NHMRC


Funding Acknowledgements

Internal sourcesThe University of Melbourne, Australia.Australian Catholic University, Australia.External sourcesNational Health and Medical Research Council (NHMRC), Australia.This review is undertaken as part of a 2015 NHMRC Translating Research Into Practice (TRIP) Fellowship (APP1091833, CIA: Dr Laura Downie).National Institute for Health Research (NIHR), UK.Richard Wormald, Co-ordinating Editor for Cochrane Eyes and Vision (CEV) acknowledges financial support for his CEV research sessions from the Department of Health through the award made by the NIHR to Moorfields Eye Hospital NHS Foundation Trust and UCL Institute of Ophthalmology for a Specialist Biomedical Research Centre for Ophthalmology.This review was supported by the NIHR, via Cochrane Infrastructure funding to the CEV UK editorial base. The views expressed in this publication are those of the authors and not necessarily those of the NIHR, NHS, or the Department of Health.